AMD says overclocking blows a hidden fuse on Ryzen Threadripper 7000 to show if you’ve overclocked the chip, but it doesn’t automatically void your CPU’s warranty::AMD explains the hidden fuses behind Ryzen Threadripper 7000 processors and how it will handle warranty claims.
Why not if you’ve got thermal space to use? Overclocking will help with single-core applications where it would struggle more otherwise. It’s also just a general boost to performance for free.