The fraud surrounding Alzheimer’s research continues… Not too long ago the fraud was related to amyloid (archive version). That article was even written by the same author and features many of the same investigators.

I work in Pharma R&D (on the manufacturing side) and the company I work for has run trials for Alzheimer’s products based on research that has since been found to be fraudulent. As a published scientist myself, I would like to think that this level of manipulation and fabrication is the exception rather than the rule. However, I do think it is worth asking at this point what it is about Alzheimer’s research in particular that has led to this being so prevalent and, more importantly, so impactful. Basically, how did it go so far before anything was caught?

I suspect at least part of the answer is due to the large influx of money into the field. Researchers were tripping over themselves to earn those grants and then, once they had them, produce results to keep them. I am not in academia, so I don’t have great insight into the NIH, NIA or their processes, but this should be a wake up call to put up a certain amount of guard rails.

!lightnovels@ani.social for light novels from Japan

!aoblightnovel@bookwormstory.social for Ascendance of a Bookworm specifically (which just recently published its final volume).

Two that are local to me:

• !boston@lemmy.world
• !massachusetts@lemmy.world

@borebore@lemmy.world does an admirable job with these two. I try to chime in when I can, but am mostly busy with the communities I am running elsewhere.

I think that user donations are easier when an instance has a good focus. There are some other instances I can think of where the donation model has been enough to cover things. In addition to feddit.dk and beehaw, an instance I use most of the time, ani.social, is more than covered by donations last I checked. It looks like @hitagi@ani.social even took away the donate link in the sidebar. Never mind, I am just blind. I didn’t notice the little Ko-fi badge at the bottom. I was looking for a text link.

There is a lot of collaboration between the different instance admins in this regard. The lemmy.world admins have a matrix room that is chock full of other instance admins where they share bots that they find to help do things like find similar posters and set up filters to block things like spammy urls. The nice thing about it all is that I am not an admin, but because it is a public room, anybody can sit in there and see the discussion in real time. Compare that to corporate social media like reddit or facebook where there is zero transparency.

This is what I do. I have a VPS that handles all the 443 traffic and then proxies it back to my home server on the correct port. I also just serve some things directly from the VPS since I have it already. It also works well to have a second box for things like uptime monitoring.

Yeah, spoiler tags are the one big feature that is missing. There are also some minor things on the moderation side that aren’t there. For example, admin accounts don’t have a full list of options in the moderation menu.

Thanks for the clarification!

I am guessing a large portion of those might be inactive accounts as well. When the reddit exodus was at its peak, there were definite issues with the way 2FA worked in lemmy. I think it got reset at one point due to changes made in subsequent lemmy versions and users had to re-enable it.

One recent example from a game that I ran is that my players caused a dust explosion using flour. I had to do some quick googling to figure out how big that might be to best gauge the damage (turns out it can be pretty big), but I awarded inspiration for the creativity (despite getting caught up in the blast themselves). This was also a bit of irony since the people they were attacking were assassins that ran a bakery as cover.

Sorry for not being clear. I was referring to the discussion threads created by @rikka@ani.social in the anime community. So far, she has been creating discussion threads for the episodes in the general community (episode 4 link for reference). In the past, I have disabled these posts for certain shows if there is a dedicated community to the show that wants to run their own discussion posts (!dungeonmeshi@ani.social did this for instance).

Note if it wasn’t clear: I am a mod of the anime community and the maintainer of the rikka bot.

Feel free to make a promo post over in !anime@ani.social as well. Good luck with things! I don’t want to switch it up partway through the season, but if there is ever a season 2 and you want to run your own episode threads instead of the bot-created ones, let me know.

Some good answers in here already. It boils down to a couple points for me:

• Back when I started selfhosting, it was either nginx or apache, and I found nginx better and easier to set up
• All the nginx knowledge I learned years ago still works just the same as it did back then, so why potentially mess things up by switching if it all still works
• Basically every project has an example nginx config for reference, that can’t be said about other proxies
• It is easier to find support online for edge cases that might pop up with nginx due to the ubiquity of its use and years of history

Intel confirmed on reddit that oxidation did impact some chips.

More than one thing can be wrong at the same time, so everybody can be right!

I didn’t have a VPS with them, but long ago I had a couple domains through them. One of them had an issue with the auto-renewal and I never got a notification of any kind, only finding out when they had taken ownership of the domain, advertising it for sale. Then they wanted some way, way higher amount of money for me to buy it back. So, I don’t have any domains with them any more.

This was years and years ago though, so they might be better now.

Everybody’s pager went off in celebration!

I use Sonarr, but it does mess up sometimes for shows even when you mark it as an anime to use absolute numbering. It most often happens with older shows that have lots of OVAs that are sometimes listed as episodes and sometimes listed as specials, depending on the database. So, if you are having Sonarr manage your downloads, then it can grab the wrong episode if its database (I think TVDB) and the release (usually using MAL numbering) disagree.

I don’t have a solution for you, but I will be watching this thread. Currently, I use Sonarr for library organization, but it doesn’t always work well with anime due to title differences and differences between how seasons/specials are numbered in different databases. So, Shoko was on my radar to try out at some point since it uses anidb.

I used to have my docker updates done automatically. However, as the services I used to run just for myself have started to be used by other people (family, friends), I am less tolerant of having things break. So, instead of something like watchtower, I run diun these days. I have it set up to ping me in a discord channel when a docker update is available. Then, I can actually perform the update when I have time and attention to troubleshoot any issues that may come up.

I haven’t seen this one, but the review definitely makes me interested. I am a total sucker for a well-done romance. Back when the show came out (2007) that was absolutely not the case, so I had skipped it. Might have to go back and check it out.

BTW, I see you crossposted a bunch of different communities. This would also fit right in on !anime@ani.social, so feel free to add that one to your list.